Leveraging emerging technologies and a global competitive advantage, the ARC Centre of Excellence for Advanced Peptide and Protein Engineering aims to transform the engineering and translation of peptides and proteins – molecules essential for all life on Earth – for human and planetary benefit. CAPE will uncover unique molecules, including from Australia’s flora and fauna, using advanced computational methods; design ‘new-to-nature’ structures with unprecedented applications; and step-change production technologies to an automated and eco-friendly new paradigm. CAPE will unite diverse research leaders for a legacy of impactful translation in agriculture, conservation and biotech, while engaging the Australian public in the peptide and protein revolution via extensive outreach and creative pedagogy. Funding: $35 million over 7 years Centre Director: Prof Richard Payne Administering Organisation: The University of Sydney Participating Organisations: The Australian National University The University of Queensland Queensland University of Technology Monash University Stanford University Yale University, USA University of Illinois at Urbana-Champaign University of California, Davis Massachusetts Institute of Technology University of Pennsylvania, USA The Rockefeller University University of Tokyo University of Cambridge, UK Imperial College London The Rosalind Franklin Institute University of Zurich, Switzerland Indian Institute of Technology, Kanpur The Walter and Eliza Hall Institute of Medical Research Novo Nordisk A/S AstraZeneca, Sweden Genentech Inc Merck Sharp and Dohme UK Limited NOVARTIS PHARMACEUTICALS AUSTRALIA PTY LIMITED Syngenta Crop Protection Commonwealth Scientific and Industrial Research Organisation INSAMO SOUTH PTY LTD Unnatural Products Neoculi Pty Ltd MICROBIAL SCREENING TECHNOLOGIES PTY. LTD. Aralez Bio INNOVATE AG PTY LIMITED PHYLLOME PTY LTD FLOW-AI PTY LTD SHIMADZU MEDICAL SYSTEMS (OCEANIA) PTY LIMITED Tecan Australia Pty Ltd Vapourtec Ltd Opentrons Labworks Inc. Biotage Sweden AB Amide Technologies Cytiva Bioplatforms Australia Ltd DEADLYSCIENCE LTD TARONGA CONSERVATION SOCIETY AUSTRALIA